- + Audio Highlights—Listen to the JAMA Editor’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA.
- + JAMA
- + Study: Bird Flu in Dairy Cows May Spread More Easily to Other Mammals—Certain characteristics of the highly pathogenic avian influenza A(H5N1), or H5N1 bird flu, in dairy cows may make it easier to transmit the virus to ...
- + GLP-1 RA Drugs Not Associated With Increased Suicidal Thoughts—Given the past decade’s dramatic increase in glucagon-like peptide-1 receptor agonist (GLP-1 RA) use among people with type 2 diabetes, clinicians hav...
- + One in 5 Children Have Autism If Older Sibling Does Too—Roughly 20% of younger siblings of children with autism spectrum disorder (ASD) were later diagnosed themselves, a new study on familial recurrence of...
- + New Immunotherapy Shows Potential to Shrink Metastatic Solid Tumors—A new personalized immunotherapy using engineered white blood cells successfully shrank solid cancerous tumors in some patients, a study published in ...
- + Less Screen Time Linked to Improved Sociability and Behavior in Children—Reducing leisure screen time to just a few hours a week could decrease behavioral issues and increase positive social interactions for children and ad...
- + WHO Approves First Self-Test for Hepatitis C—In July, the World Health Organization (WHO) prequalified the first hepatitis C virus (HCV) self-test. The product, called OraQuick HCV self-test, is ...
- + Mediterranean Diet Linked to Better Heart Health in Children and Teens—The Mediterranean diet, which emphasizes eating more fruits, vegetables, legumes, and healthy fats, has already been associated with health benefits f...
- + Study: Secondhand Tobacco Smoke Worse for Children Than E-Cigarette Vapo—Children absorb much less nicotine from secondhand e-cigarette vapor than from secondhand tobacco smoke, according to a study of roughly 1800 children...
- + US Surgeon General Calls for Social Media Warning Labels—This Medical News article is an interview with US Surgeon General Vivek Murthy, MD, MBA, and JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MA...
- + E-Cigarette Use in Adolescents and Adults—The introduction of electronic cigarettes (e-cigarettes) in recent years has created new dilemmas for clinical and research communities. E-cigarettes ...
- + Vaping in Youth—This JAMA Insights reviews the health effects of vaping among youth in the US and current recommendations for screening and treatment.
- + Controversial FDA Decision Authorizes Menthol-Flavored E-Cigarettes—This Medical News story examines the controversy surrounding the FDA’s first authorization of flavored e-cigarettes, in this case menthol.
- + Pulmonary Vein Isolation and Left Atrial Appendage Ligation in Atrial Fibrillation—To the Editor A recent study investigated the safety and effectiveness of percutaneous left atrial appendage (LAA) ligation with catheter pulmonary ve...
- + Review of Systemic Lupus Erythematous—To the Editor A recent Review provided comprehensive information about the manifestations and treatment options for patients with systemic lupus eryth...
- + Pulmonary Vein Isolation and Left Atrial Appendage Ligation in Atrial Fibrillation—Reply—In Reply Drs Xia and Su raise several queries about our study, the aMAZE trial. First, they state, “The study did not assess left atrial appendage ele...
- + Review of Systemic Lupus Erythematous—Reply—In Reply The Letter to the Editor from Dr Watkins and colleagues about our Review on SLE raises the important topic of congenital heart block risk for...
- + Oral Antibiotics and Risk of Serious Cutaneous Adverse Drug Reactions—This population-based case-control study assesses the association of commonly prescribed oral antibiotics with serious cutaneous adverse drug reaction...
- + Both Sides Now—In this narrative medicine essay, a pediatric and internal medicine physician and her husband reach a difficult crossroads upon learning that their un...
- + How Should Organizations Be Held Accountable for Clinician Well-Being?—This Viewpoint summarizes methods used by health care organizations to assess and improve clinician well-being, discusses the potential downsides of p...
- + Supporting Adolescents’ Desire to Quit E-Cigarettes—Electronic cigarettes (e-cigarettes) are the most widely used tobacco/nicotine product among US middle and high school adolescents. According to data ...
- + E-Cigarette Use in Adults—This JAMA Insights explores the adverse effects and health outcomes of e-cigarettes vs combusted cigarettes and the effectiveness of using e-cigarette...
- + “Denicotinized” Tobacco—Mankind has traditionally included in the daily regimen a variety of substances that do not function as true nutrients. Some of them are so unlike the...
- + Variability in Constituents of E-Cigarette Products Containing Nicotine Analogues—This study characterizes and quantifies constituents in 2 e-cigarette products to assess product consistency and inform future risk assessments.
- + Vaping Cessation Text Messaging Intervention for Adolescent E-Cigarette Users—This randomized clinical trial compares the effectiveness of a tailored, interactive text message program for nicotine vaping cessation vs assessment ...
- + Patient Information: E-Cigarettes—This JAMA Patient Page describes e-cigarettes and the potential health effects of vaping.
- + Prediction Models for Individualized Treatment Effects of Oxygen Targets—To the Editor A recent study by Dr Buell and colleagues addresses an important aspect of care in the intensive care unit (ICU), individualized oxygena...
- + Prediction Models for Individualized Treatment Effects of Oxygen Targets—Reply—In Reply We appreciate the letter to the editor by Dr Tu and colleagues regarding our recent analysis of 2 randomized trials to derive and externally ...
- + Laertes Loses His Memory—She yelled at me this morning when I walked to the kitchen with my dirty laundry and put it in the trash can.
- + Obesity in Adolescents: A Review—This Review summarizes the current evidence regarding the epidemiology, pathophysiology, diagnosis, and treatment of obesity in adolescents, with a fo...
- + High Prices for Gene Therapies in Sickle Cell Disease—This Viewpoint discusses the high cost of new gene therapies for sickle cell disease, the challenges these costs pose for health care access, and new ...
- + Prevalence of Nicotine Pouch Use Among US Adults—This cross-sectional study uses data from the 2022 Tobacco Use Supplement of the Current Population Survey to estimate the prevalence of adult US nico...
- + Major Gaps in the Cascade of Care for Opioid Use Disorder—This Viewpoint examines a recent report that used data from the 2022 National Survey on Drug Use and Health to estimate the opioid cascade of care, a ...
- + Checks and Balances on FDA’s Authority—In this Viewpoint, the authors refute recent suggestions that the US Food and Drug Administration (FDA) is not accountable for its decisions, pointing...
- + Germline CDH1 Variants and Lifetime Cancer Risk—This cross-sectional study describes the risk estimates for gastric and breast cancer for individuals with CDH1 variants.
- + Guidance on Reporting Gender, Sex, Gender Identity, Sexual Orientation, and Age—As we have previously acknowledged, terminology, usage, and word choice are critically important in medical and scientific publication, particularly w...
- + Audio Highlights—Listen to the JAMA Editor’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA.
- + JAMA
- + NIH Starts Testing Nasal COVID-19 Vaccine in US—A clinical trial evaluating the safety and effectiveness of a nasal vaccine candidate known as MPV/S-2P to protect against COVID-19 recently began enr...
- + EHR Data Suggest Tirzepatide Outdoes Semaglutide for Weight Loss—People with overweight or obesity who used tirzepatide lost about 7% more weight during the year after beginning treatment compared with those who use...
- + Systematic Review: Problems With Smell Tied to Increased Frailty Risk—People with a reduced sense of smell had more than twice the risk of frailty than those with a normal one, according to an analysis of 10 studies publ...
- + WHO Launches First Global Guidelines for Quitting Tobacco—The World Health Organization (WHO) recently introduced its first set of recommendations aimed at helping adults quit tobacco—a “milestone in our glob...
- + Prenatal RSV Vaccine Not Tied to Higher Risk of Preterm Births—Children born to people who had received a respiratory syncytial virus prefusion F (RSVpreF) vaccine during pregnancy were well-protected against seve...
- + Weight Loss Drugs Linked With Lower Risk of 10 Cancers—People with type 2 diabetes who used glucagon-like peptide 1 receptor agonists (GLP-1 RAs) had a lower risk of 10 types of so-called obesity-associate...
- + Dementia Rates Have Fallen Over Time, But Some Risk Factors Are Rising—The proportion of people diagnosed with and living with dementia has decreased over time in the US and in several European countries, according to a r...
- + Pharmacy Middlemen Profit at Patients’ Expense, Says FTC—In 2022, the US Federal Trade Commission (FTC) launched an inquiry into the opaque business practices of pharmacy benefit managers (PBMs), which act a...
- + More Data About Risks, Benefits Might Change Breast Cancer Screening Choice—In April 2024, the US Preventive Services Task Force (USPSTF) recommended that women aged 40 to 74 years with an average risk of breast cancer undergo...
- + Progress Toward A Staph Vaccine—This Medical News article discusses recent findings that help explain Staphylococcus aureus vaccine failures.
- + A Surge in Ransomware Attacks Threatens Health Systems and Patient Care—This Medical News story discusses the rise in ransomware cyberattacks on health care, as well as new cybersecurity initiatives.
- + Hospital Assets Before and After Private Equity Acquisition—This study assesses changes in hospitals’ capital assets after private equity acquisition.
- + Enhancing Obstetric Ultrasonography With Artificial Intelligence in Resource-Limited Settings—Establishing gestational age (GA) is critical for guiding obstetric care and decision-making (including the timing of prenatal visits, laboratory test...
- + Industrial Pollution of Human Environment—The survival of man depends on his ability to adapt himself to his environment. For thousands of years changes in man’s environment resulted from natu...
- + Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Ultrasound Sweeps—This prospective diagnostic study examines the accuracy of an AI-enabled ultrasonography tool in estimating gestational age when used by those with no...
- + Patient Information: What Are Canker Sores?—This JAMA Patient Page describes the types of canker sores and how they can be treated.
- + New Rules Requiring Accessible Medical Diagnostic Equipment—This Viewpoint reviews the history of mandates governing access to medical diagnostic equipment in Section 504 of the Rehabilitation Act of 1973 and r...
- + Access to Psychiatric Appointments for Medicaid Enrollees in 4 US Cities—This audit study examines availability of and wait times for Medicaid enrollee appointments with psychiatric prescribing clinicians across 4 of the mo...
- + GLP-1 Agonists for Obesity—To the Editor In his Viewpoint, Dr Mozaffarian summarizes the problematic issues related to using GLP-1 agonists for weight loss, including the high p...
- + GLP-1 Agonists for Obesity—To the Editor Dr Mozaffarian’s Viewpoint proposing a new solution to the cost and access issues plaguing GLP-1 agonists for weight loss contains serio...
- + GLP-1 Agonists for Obesity—To the Editor We read with interest the article by Dr Mozaffarian concerning the role of glucagon-like peptide 1 (GLP-1) agonists in the treatment of ...
- + GLP-1 Agonists for Obesity—To the Editor A recent Viewpoint questions the long-term viability of GLP-1 agonists. Rather than continuing pharmacotherapy after initial weight loss...
- + GLP-1 Agonists for Obesity—Reply—In Reply Dr Kurian and colleagues raise the option of surgical obesity treatments. These can be effective and cost-effective for individuals with appr...
- + wasn’t there once—in winter the bones of camellias jut along your roof, arms spare but womanly—some trees take time dying. for years I visited you, watched you unravel ...
- + The Body as Poetry—Because its most defining characteristics lend it physicality, such as the heartbeat of meter and the shapeliness of stanzaic structure, poetry is a u...
- + Oaths, Conscience, Contracts, and Laws—This Viewpoint explains the 3 trends—personal conscience, employment contracts, and laws—that challenge physicians from putting their patients first a...
- + Midcareer Satisfaction and Likelihood of Leaving Current Position—This study assesses career satisfaction, discrepancies between ideal and expected careers, and likelihood of leaving current positions among former K ...
- + Detection of Phosphorylated α-Synuclein—To the Editor We have some concerns about a recent study about phosphorylated α-synuclein as a diagnostic biomarker for synucleinopathies.
- + Detection of Phosphorylated α-Synuclein—Reply—In Reply We appreciate the Letter by Dr Tu and colleagues about our article on skin biopsy detection of P-SYN. We agree that P-SYN deposition within t...
- + Heat-Related Illness in Athletes—This JAMA Insights discusses heat-related illness in athletes, including risk factors, prevention, symptoms, and management.
- + Anterior Cruciate Ligament Injuries in Female Athletes—This JAMA Insights discusses anterior cruciate ligament (ACL) injuries in female athletes, including modifiable and nonmodifiable sex-based risk facto...
- + Trail Magic—In this narrative medicine essay, an obstetrician-gynecologist describes a day in her life of crossing state lines to provide abortion care for people...
- + Migration Stigma, US Politics, and Health—This Viewpoint discusses stigma and health consequences associated with migration in the context of the US election and identifies ways to develop str...
- + Guns, Hospitals, and “Sensitive Places”—This Special Communication explores whether US hospitals fall under the “sensitive places” exception to the Second Amendment and the ethical and pract...
- + Supporting OB-GYNs in Abortion-Restrictive States—This Viewpoint provides proposed institutional practices, such as medicolegal collaboration and providing materials and resources, to support obstetri...
- + Resolving the Dilemma on Continuous vs Intermittent β-Lactam Antibiotics in Sepsis—The Surviving Sepsis Campaign guidelines recommend that adults with sepsis or septic shock should receive prolonged infusion of β-lactams (after an in...
- + Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis—This clinical trial compares the efficacy of continuous vs intermittent infusion of a β-lactam antibiotic (piperacillin-tazobactam or meropenem) in de...
- + Prolonged vs Intermittent Infusions of β-Lactam Antibiotics in Adults With Sepsis or Septic Shock—This systematic review and bayesian meta-analysis investigated whether administration of β-lactam antibiotics by prolonged infusion reduces 90-day mor...
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